Please help..Clickspring + others

My husband's computer has been seriously infected for awhile now (my brother doesn't know not to click on *win a free playstation*) and i keep finding all sorts of crap on here. Can anyone give me a hand? I keep gettinc clickspring, plus others that occasionally come up. Any help will be rewarded with a hug and a hearty thanks...

Logfile of HijackThis v1.99.1
Scan saved at 6:35:35 PM, on 11/1/2005
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\PROGRA~1\COMMON~1\AOL\ACS\AOLacsd.exe
C:\WINDOWS\system32\CTsvcCDA.EXE
c:\PROGRA~1\mcafee.com\vso\mcvsrte.exe
C:\PROGRA~1\McAfee.com\PERSON~1\MPFSERVICE.exe
C:\WINDOWS\system32\tcpsvcs.exe
C:\WINDOWS\system32\MsPMSPSv.exe
c:\PROGRA~1\mcafee.com\vso\mcshield.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\hkcmd.exe
C:\Program Files\Java\j2re1.4.2_03\bin\jusched.exe
C:\Program Files\Intel\Modem Event Monitor\IntelMEM.exe
C:\Program Files\Creative\Sound Blaster Live! 24-bit\Surround Mixer\CTSysVol.exe
C:\WINDOWS\system32\Rundll32.exe
C:\Program Files\Real\RealPlayer\RealPlay.exe
C:\WINDOWS\system32\dla\tfswctrl.exe
C:\Program Files\Common Files\InstallShield\UpdateService\issch.exe
C:\PROGRA~1\mcafee.com\agent\mcagent.exe
C:\PROGRA~1\mcafee.com\vso\mcvsshld.exe
C:\PROGRA~1\McAfee.com\PERSON~1\MpfTray.exe
C:\PROGRA~1\mcafee.com\mps\mscifapp.exe
C:\Program Files\Common Files\AOL\1130225838\ee\AOLHostManager.exe
c:\progra~1\mcafee.com\vso\mcvsescn.exe
C:\Program Files\Common Files\AOL\1130225838\ee\AOLServiceHost.exe
C:\PROGRA~1\McAfee.com\PERSON~1\MpfAgent.exe
c:\progra~1\mcafee.com\vso\mcvsftsn.exe
c:\program files\common files\aol\1130225838\ee\services\antiSpywareApp\ver2_0_7\AOLSP Scheduler.exe
C:\Program Files\Common Files\AOL\1130225838\ee\AOLServiceHost.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Yahoo!\Messenger\ymsgr_tray.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Documents and Settings\Thomas\Desktop\HijackThis1991.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.yahoo.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = http://us.rd.yahoo.com/customize/ie/defaults/sb/msgr7/*http://www.yahoo.com/ext/search/search.html
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = http://us.rd.yahoo.com/customize/ie/defaults/su/msgr7/*http://www.yahoo.com
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 6.0\Reader\ActiveX\AcroIEHelper.dll
O2 - BHO: McBrwHelper Class - {227B8AA8-DAF2-4892-BD1D-73F568BCB24E} - c:\program files\mcafee.com\mps\mcbrhlpr.dll
O2 - BHO: McAfee PopupKiller - {3EC8255F-E043-4cae-8B3B-B191550C2A22} - c:\program files\mcafee.com\mps\popupkiller.dll
O2 - BHO: DriveLetterAccess - {5CA3D70E-1895-11CF-8E15-001234567890} - C:\WINDOWS\system32\dla\tfswshx.dll
O3 - Toolbar: McAfee VirusScan - {BA52B914-B692-46c4-B683-905236F6F655} - c:\progra~1\mcafee.com\vso\mcvsshl.dll
O4 - HKLM\..\Run: [IgfxTray] C:\WINDOWS\system32\igfxtray.exe
O4 - HKLM\..\Run: [HotKeysCmds] C:\WINDOWS\system32\hkcmd.exe
O4 - HKLM\..\Run: [SunJavaUpdateSched] C:\Program Files\Java\j2re1.4.2_03\bin\jusched.exe
O4 - HKLM\..\Run: [IntelMeM] C:\Program Files\Intel\Modem Event Monitor\IntelMEM.exe
O4 - HKLM\..\Run: [CTSysVol] C:\Program Files\Creative\Sound Blaster Live! 24-bit\Surround Mixer\CTSysVol.exe /r
O4 - HKLM\..\Run: [P17Helper] Rundll32 P17.dll,P17Helper
O4 - HKLM\..\Run: [UpdReg] C:\WINDOWS\UpdReg.EXE
O4 - HKLM\..\Run: [RealTray] C:\Program Files\Real\RealPlayer\RealPlay.exe SYSTEMBOOTHIDEPLAYER
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [dla] C:\WINDOWS\system32\dla\tfswctrl.exe
O4 - HKLM\..\Run: [ISUSPM Startup] C:\PROGRA~1\COMMON~1\INSTAL~1\UPDATE~1\ISUSPM.exe -startup
O4 - HKLM\..\Run: [ISUSScheduler] "C:\Program Files\Common Files\InstallShield\UpdateService\issch.exe" -start
O4 - HKLM\..\Run: [VSOCheckTask] "c:\PROGRA~1\mcafee.com\vso\mcmnhdlr.exe" /checktask
O4 - HKLM\..\Run: [MCAgentExe] c:\PROGRA~1\mcafee.com\agent\mcagent.exe
O4 - HKLM\..\Run: [MCUpdateExe] C:\PROGRA~1\mcafee.com\agent\McUpdate.exe
O4 - HKLM\..\Run: [VirusScan Online] c:\PROGRA~1\mcafee.com\vso\mcvsshld.exe
O4 - HKLM\..\Run: [MPFExe] C:\PROGRA~1\McAfee.com\PERSON~1\MpfTray.exe
O4 - HKLM\..\Run: [MPSExe] c:\PROGRA~1\mcafee.com\mps\mscifapp.exe /embedding
O4 - HKLM\..\Run: [HostManager] C:\Program Files\Common Files\AOL\1130225838\ee\AOLHostManager.exe
O4 - HKCU\..\Run: [Yahoo! Pager] C:\Program Files\Yahoo!\Messenger\ypager.exe -quiet
O4 - Global Startup: America Online 9.0 Tray Icon.lnk = C:\Program Files\America Online 9.0\aoltray.exe
O4 - Global Startup: Giggles.lnk = C:\Program Files\OracleOfDelphi\Giggles\giggles.exe
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\j2re1.4.2_03\bin\npjpi142_03.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\j2re1.4.2_03\bin\npjpi142_03.dll
O9 - Extra button: Real.com - {CD67F990-D8E9-11d2-98FE-00C0F0318AFE} - C:\WINDOWS\system32\Shdocvw.dll
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O16 - DPF: {30528230-99f7-4bb4-88d8-fa1d4f56a2ab} (YInstStarter Class) - C:\Program Files\Yahoo!\Common\yinsthelper.dll
O16 - DPF: {4ED9DDF0-7479-4BBE-9335-5A1EDB1D8A21} (McAfee.com Operating System Class) - http://download.mcafee.com/molbin/shared/mcinsctl/en-us/4,0,0,90/mcinsctl.cab
O16 - DPF: {9A9307A0-7DA4-4DAF-B042-5009F29E09E1} (ActiveScan Installer Class) - http://acs.pandasoftware.com/activescan/as5free/asinst.cab
O16 - DPF: {BCC0FF27-31D9-4614-A68E-C18E1ADA4389} (DwnldGroupMgr Class) - http://download.mcafee.com/molbin/shared/mcgdmgr/en-us/1,0,0,23/mcgdmgr.cab
O20 - Winlogon Notify: igfxcui - C:\WINDOWS\SYSTEM32\igfxsrvc.dll
O23 - Service: AOL Connectivity Service (AOL ACS) - America Online, Inc. - C:\PROGRA~1\COMMON~1\AOL\ACS\AOLacsd.exe
O23 - Service: Creative Service for CDROM Access - Creative Technology Ltd - C:\WINDOWS\system32\CTsvcCDA.EXE
O23 - Service: McAfee.com McShield (McShield) - Unknown owner - c:\PROGRA~1\mcafee.com\vso\mcshield.exe
O23 - Service: McAfee SecurityCenter Update Manager (mcupdmgr.exe) - McAfee, Inc - C:\PROGRA~1\McAfee.com\Agent\mcupdmgr.exe
O23 - Service: McAfee.com VirusScan Online Realtime Engine (MCVSRte) - Networks Associates Technology, Inc - c:\PROGRA~1\mcafee.com\vso\mcvsrte.exe
O23 - Service: McAfee Personal Firewall Service (MpfService) - McAfee Corporation - C:\PROGRA~1\McAfee.com\PERSON~1\MPFSERVICE.exe
O23 - Service: Intel NCS NetService (NetSvc) - Intel(R) Corporation - C:\Program Files\Intel\PROSetWired\NCS\Sync\NetSvc.exe

Thank ya in advance for any and all help.
Foppalady