Quoting Buddy J
We've got pets and I still roll with the door off on my case. I still like a vertical motherboard for daily use. The smaller footprint it affords gives me back valuable desk space. I've got my personal tower and the NZXT Panzerbox side-by-side on the desk right now.
Your pets will stay away. They aren't terribly interested in things like that. I have a couple of overly curious kittens that don't understand such concepts as "stay away from the shiny/moving things". They sit and stare at the ceiling fan and every once in a while try to get to it.
I'd love to get this case though. How is it for moving around? Seems like it could be good for a portable LAN system, though airport security might get a little curious.