spyware, trojans help me please!

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I have been hijacked and have some spyware that i cant remove i have tried everything spybot, SCWshredder but there are some really anoying popups that keep poping up along with trojans. please help me get rid of this here is my log:

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\SOUNDMAN.EXE
C:\PROGRA~1\CA\ETRUST~1\realmon.exe
C:\WINDOWS\System32\gofxip.exe
C:\Program Files\QuickTime\qttask.exe
C:\Documents and Settings\Peter\Application Data\nwlm.exe
C:\WINDOWS\System32\aqvi.exe
C:\Program Files\CA\eTrust Antivirus\InoRpc.exe
C:\Program Files\CA\eTrust Antivirus\InoRT.exe
C:\Program Files\CA\eTrust Antivirus\InoTask.exe
C:\Program Files\CA\SharedComponents\CA_LIC\LogWatNT.exe
C:\WINDOWS\System32\nvsvc32.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\wuauclt.exe
C:\Program Files\MSN Messenger\msnmsgr.exe
C:\Program Files\Internet Explorer\IEXPLORE.EXE
C:\Program Files\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName = Koppelingen
R3 - Default URLSearchHook is missing
O2 - BHO: MxTargetObj Class - {0000607D-D204-42C7-8E46-216055BF9918} - C:\WINDOWS\mxTarget.dll
O2 - BHO: hbclobj Class - {2E77E33F-671E-4334-ABAA-0C2E2BE654F1} - C:\WINDOWS\System32\mdv_32.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: (no name) - {65FC3805-EC3A-2FBA-8056-16550FA02911} - C:\WINDOWS\System32\lxcezfy.dll
O2 - BHO: Cls - {CF021F40-3E14-23A5-CBA2-717765721306} - C:\WINDOWS\System32\wer1306.dll
O4 - HKLM\..\Run: [SoundMan] SOUNDMAN.EXE
O4 - HKLM\..\Run: [NeroCheck] C:\WINDOWS\System32\\NeroCheck.exe
O4 - HKLM\..\Run: [Realtime Monitor] C:\PROGRA~1\CA\ETRUST~1\realmon.exe -s
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\System32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [AntivirusRegistration] C:\Program Files\Excid.com Aps\eTrust Antivirus Registration\EzAntivirusRegistrationCheck.exe
O4 - HKLM\..\Run: [hcvqpglwcyjue] C:\WINDOWS\System32\gofxip.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [pkl] C:\WINDOWS\System32\pkl.exe
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
O4 - HKCU\..\Run: [Trdc] C:\Documents and Settings\Peter\Application Data\nwlm.exe
O4 - HKCU\..\Run: [Qepy] C:\WINDOWS\System32\aqvi.exe