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Help please! Slow comp

My vista is running very slowly... Here's the log.
Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 6:54:48 PM ? mel, on 12/30/2008
Platform: Windows Vista (WinNT 6.00.1904)
MSIE: Internet Explorer v7.00 (7.00.6000.16764)
Boot mode: Normal

Running processes:
c:\PROGRA~1\mcafee.com\agent\mcagent.exe
C:\Windows\system32\taskeng.exe
C:\Windows\System32\rundll32.exe
C:\Program Files\DellTPad\ApMsgFwd.exe
C:\Program Files\DellTPad\Apntex.exe
C:\Program Files\DellTPad\HidFind.exe
C:\Windows\system32\Dwm.exe
C:\Windows\explorer.exe
C:\Program Files\Mozilla Firefox\firefox.exe
C:\PROGRA~1\mcafee\msc\mcshell.exe
c:\PROGRA~1\mcafee\VIRUSS~1\mcvsshld.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

F2 - REG:system.ini: UserInit=userinit.exe,
O1 - Hosts: ::1 localhost
O2 - BHO: Thunder AtOnce - {01443AEC-0FD1-40fd-9C87-E93D1494C233} - C:\Program Files\Thunder\ComDlls\TDAtOnce_Now.dll
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: RealPlayer Download and Record Plugin for Internet Explorer - {3049C3E9-B461-4BC5-8870-4C09146192CA} - C:\Program Files\Real\RealPlayer\rpbrowserrecordplugin.dll
O2 - BHO: McAntiPhishingBHO - {377C180E-6F0E-4D4C-980F-F45BD3D40CF4} - c:\PROGRA~1\mcafee\msk\mcapbho.dll
O2 - BHO: Groove GFS Browser Helper - {72853161-30C5-4D22-B7F9-0BBC1D38A37E} - C:\Program Files\Microsoft Office\Office12\GrooveShellExtensions.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0\bin\ssv.dll
O2 - BHO: scriptproxy - {7DB2D5A0-7241-4E79-B68D-6309F01C5231} - C:\Program Files\McAfee\VirusScan\scriptsn.dll
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O2 - BHO: ThunderBHO - {889D2FEB-5411-4565-8998-1DD2C5261283} - C:\Program Files\Thunder\ComDlls\xunleiBHO_Now.dll
O2 - BHO: Windows Live Sign-in Helper - {9030D464-4C02-4ABF-8ECC-5164760863C6} - C:\Program Files\Common Files\Microsoft Shared\Windows Live\WindowsLiveLogin.dll
O4 - HKLM\..\Run: [Windows Defender] %ProgramFiles%\Windows Defender\MSASCui.exe -hide
O4 - HKLM\..\Run: [Apoint] C:\Program Files\DellTPad\Apoint.exe
O4 - HKLM\..\Run: [OEM02Mon.exe] C:\Windows\OEM02Mon.exe
O4 - HKLM\..\Run: [SigmatelSysTrayApp] %ProgramFiles%\SigmaTel\C-Major Audio\WDM\sttray.exe
O4 - HKLM\..\Run: [NvSvc] RUNDLL32.EXE C:\Windows\system32\nvsvc.dll,nvsvcStart
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\Windows\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [NvMediaCenter] RUNDLL32.EXE C:\Windows\system32\NvMcTray.dll,NvTaskbarInit
O4 - HKLM\..\Run: [NVHotkey] rundll32.exe C:\Windows\system32\nvHotkey.dll,Start
O4 - HKLM\..\Run: [DELL Webcam Manager] "C:\Program Files\Dell\Dell Webcam Manager\DellWMgr.exe" /s
O4 - HKLM\..\Run: [Logitech Hardware Abstraction Layer] "C:\Program Files\Common Files\Logitech\khalshared\KHALMNPR.EXE"
O4 - HKLM\..\Run: [mcagent_exe] C:\Program Files\McAfee.com\Agent\mcagent.exe /runkey
O4 - HKLM\..\Run: [dscactivate] "C:\Program Files\Dell Support Center\gs_agent\custom\dsca.exe"
O4 - HKLM\..\Run: [Kernel and Hardware Abstraction Layer] KHALMNPR.EXE
O4 - HKLM\..\Run: [DellSupportCenter] "C:\Program Files\Dell Support Center\bin\sprtcmd.exe" /P DellSupportCenter
O4 - HKLM\..\Run: [MSConfig] "C:\Windows\System32\msconfig.exe" /auto
O4 - HKCU\..\Run: [MsnMsgr] "C:\Program Files\Windows Live\Messenger\MsnMsgr.Exe" /background
O4 - HKCU\..\Run: [DellSupportCenter] "C:\Program Files\Dell Support Center\bin\sprtcmd.exe" /P DellSupportCenter
O4 - HKCU\..\Run: [ehTray.exe] C:\Windows\ehome\ehTray.exe
O4 - HKCU\..\Run: [WMPNSCFG] C:\Program Files\Windows Media Player\WMPNSCFG.exe
O4 - HKUS\S-1-5-19\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-19\..\Run: [WindowsWelcomeCenter] rundll32.exe oobefldr.dll,ShowWelcomeCenter (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-20\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'NETWORK SERVICE')
O4 - Global Startup: Bluetooth.lnk = ?
O4 - Global Startup: Digital Line Detect.lnk = C:\Program Files\Digital Line Detect\DLG.exe
O4 - Global Startup: QuickSet.lnk = C:\Program Files\Dell\QuickSet\quickset.exe
O4 - Global Startup: SetPoint.lnk = ?%ProgramFiles%\SetPoint\SetPoint.exe
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office12\EXCEL.EXE/3000
O8 - Extra context menu item: Send image to &Bluetooth Device... - c:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie_ctx.htm
O8 - Extra context menu item: Send page to &Bluetooth Device... - c:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0\bin\npjpi160.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0\bin\npjpi160.dll
O9 - Extra button: (no name) - {09BA8F6D-CB54-424B-839C-C2A6C8E6B436} - (no file)
O9 - Extra button: Send to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~2\Office12\ONBttnIE.dll
O9 - Extra 'Tools' menuitem: S&end to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~2\Office12\ONBttnIE.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\Office12\REFIEBAR.DLL
O9 - Extra button: @btrez.dll,-4015 - {CCA281CA-C863-46ef-9331-5C8D4460577F} - c:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O9 - Extra 'Tools' menuitem: @btrez.dll,-12650 - {CCA281CA-C863-46ef-9331-5C8D4460577F} - c:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O13 - Gopher Prefix:
O15 - ESC Trusted Zone: http://*.update.microsoft.com
O18 - Protocol: grooveLocalGWS - {88FED34C-F0CA-4636-A375-3CB6248B04CD} - C:\Program Files\Microsoft Office\Office12\GrooveSystemServices.dll
O23 - Service: Andrea ST Filters Service (AESTFilters) - Andrea Electronics Corporation - C:\Windows\system32\aestsrv.exe
O23 - Service: Apple Mobile Device - Apple Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: Intel(R) PROSet/Wireless Event Log (EvtEng) - Intel Corporation - C:\Program Files\Intel\Wireless\Bin\EvtEng.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: McAfee Services (mcmscsvc) - McAfee, Inc. - C:\PROGRA~1\McAfee\MSC\mcmscsvc.exe
O23 - Service: McAfee Network Agent (McNASvc) - McAfee, Inc. - c:\PROGRA~1\COMMON~1\mcafee\mna\mcnasvc.exe
O23 - Service: McAfee Scanner (McODS) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcods.exe
O23 - Service: McAfee Proxy Service (McProxy) - McAfee, Inc. - c:\PROGRA~1\COMMON~1\mcafee\mcproxy\mcproxy.exe
O23 - Service: McAfee Real-time Scanner (McShield) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcshield.exe
O23 - Service: McAfee SystemGuards (McSysmon) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcsysmon.exe
O23 - Service: McAfee Personal Firewall Service (MpfService) - McAfee, Inc. - C:\Program Files\McAfee\MPF\MPFSrv.exe
O23 - Service: McAfee Anti-Spam Service (MSK80Service) - McAfee, Inc. - C:\Program Files\McAfee\MSK\MskSrver.exe
O23 - Service: Intel(R) PROSet/Wireless Registry Service (RegSrvc) - Intel Corporation - C:\Program Files\Intel\Wireless\Bin\RegSrvc.exe
O23 - Service: ServiceLayer - Nokia. - C:\Program Files\PC Connectivity Solution\ServiceLayer.exe
O23 - Service: SupportSoft Sprocket Service (dellsupportcenter) (sprtsvc_dellsupportcenter) - SupportSoft, Inc. - C:\Program Files\Dell Support Center\bin\sprtsvc.exe
O23 - Service: SigmaTel Audio Service (STacSV) - IDT, Inc. - C:\Windows\system32\STacSV.exe
O23 - Service: stllssvr - MicroVision Development, Inc. - C:\Program Files\Common Files\SureThing Shared\stllssvr.exe
O23 - Service: XAudioService - Conexant Systems, Inc. - C:\Windows\system32\DRIVERS\xaudio.exe

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